Artemether CAS 71963-77-4 Artemisia Annua Extract

I-Artemether yi-sesquiterpene lactone efumaneka kwiingcambu zeArtemisia annua, ngokuqhelekileyo eyaziwa ngokuba ngumhlonyane oswiti.Lichiza elinamandla lokulwa nemalariya elisetyenziselwa ukunyanga nokuthintela isifo seengcongconi.I-Artemisinin, i-precursor ye-artemether, yaqala ukutsalwa kwisityalo ngo-1970, kwaye ukufunyanwa kwayo kuzuze umphandi waseTshayina u-Tu Youyou iBhaso leNobel kuNyango ngo-2015.

I-Artemether isebenza ngokutshabalalisa iintsholongwane ezibangela isifo seengcongconi.Isifo seengcongconi sibangelwa sisifunxi-gazi esibizwa ngokuba yiPlasmodium, esisulela abantu ngokulunywa ziingcongconi eziziimazi ekuthiwa yiAnopheles.Xa sele zingenile kumhlambi womntu, ezi zifunxi-gazi ziphindaphindeka ngokukhawuleza esibindini nakwiiseli ezibomvu zegazi, nto leyo ebangela umkhuhlane, iingqele, nezinye iimpawu ezinjengomkhuhlane.Ukuba ayinyangwa, isifo seengcongconi sinokubulala.

I-Artemether isebenza kakhulu ngokuchasene neentlobo ze-Plasmodium falciparum ezinganyangekiyo ngamachiza, ebangela uninzi lokusweleka okunxulumene nemalariya kwihlabathi liphela.Ikwasebenza ngokuchasene nezinye iintlobo zePlasmodium parasites ezibanga isifo seengcongconi.I-Artemether idla ngokusetyenziswa ngokudibeneyo namanye amachiza, anjenge-lumefantrine, ukunciphisa umngcipheko wokunganyangeki ngamachiza.

Ngaphandle kokusetyenziswa kwayo njengechiza lokulwa nesifo seengcongconi, i-artemether ikwafunyaniswe inezinye iimpawu zonyango.Uphononongo lubonise ukuba ine-anti-inflammatory, anti-tumor, kunye ne-anti-viral activities.Isetyenziselwa ukunyanga isifo samathambo, i-lupus, kunye nezinye izifo ezizimele.Ikwaphandiwe amandla ayo okunyanga i-COVID-19, nangona uphando olongezelelweyo luyafuneka ukuqinisekisa ukusebenza kwayo.

I-Artemether ikhuselekile ngokubanzi kwaye inyamezeleke kakuhle xa isetyenziswa njengoko kuyalelwe.Nangona kunjalo, njengawo onke amachiza, inokubangela iziphumo ebezingalindelekanga.Ezona ziphumo bezingalindelekanga ze-artemether ziquka isicaphucaphu, ukuhlanza, isiyezi, kunye neentloko.Kwiimeko ezinqabileyo, kunokubangela iziphumo ezibi kakhulu, ezifana nokubetha kwentliziyo, ukuxhuzula, kunye nokulimala kwesibindi.

Ukuqukumbela, i-artemether lichiza elinamandla lokulwa nesifo seengcongconi elitshintshe unyango lwemalariya kunye nothintelo.Ukufunyaniswa kwayo kusindise ubomi obungenakubaleka kwaye kwafumana ukuqondwa kuluntu lwezenzululwazi.Ezinye iimpawu zonyango zenza ukuba ibe ngumviwa othembisayo wonyango lwezinye izifo.Nangona inokubangela iziphumo ebezingalindelekanga, izibonelelo zayo ziyodlula lee imingcipheko yayo xa isetyenziswa phantsi kweliso lonyango.
Iifom zedosi ezisetyenziswa ngokuqhelekileyo ziquka iipilisi, iipilisi kunye neenaliti.Iindidi zamachiza ngamachiza okulwa nesifo seengcongconi, kwaye eyona nxalenye iphambili yi-artemether.Uphawu lwe-causative yamacwecwe e-artemether yayiyipilisi ezimhlophe.Umlingiswa we-artemether capsule yi-capsule, iziqulatho zayo zingumgubo omhlophe;Uphawu lwechiza lwenaliti ye-artemether ayinambala ukuya kwioli etyheli ekhanyayo - njengolwelo.