I-Artemetheti Cas 71963-777 I-Artemisia Arteadu

I-Artemether yi-sesquiterpene i-latone ifunyenwe kwiingcambu zeI-Artemisia Anua, ebizwa ngokuba ngumhloli omnandi. Sisichiza esinamandla esilingane esisetyenziselwa ukunyanga nokuthintela isifo seengcongconi. I-Artemisinin, i-Artemisin, i-Artemimar ye-artemetive, yasungulwa kuqala kwisityalo ngo-1970, kwaye ifunyenwe ifunyenwe ngabaphandi baseTshayina ngo-2015.

I-Artemether isebenza ngokutshabalalisa amabala anezinto ezinoxanduva lokubangela isifo seengcongconi. Imalariya ibangelwa yiparasite ye-protozoan ebizwa ngokuba yiPlasmodium, edluliselwe ebantwini ngokuluma kwe-anoriocious onosulelekileyo. Kanye ngaphakathi komkhosi womntu, iiparasites ziphindaphindwe ngokukhawuleza kwisibindi kunye neeseli ezibomvu zegazi, zibangela umkhuhlane, i-chills, kunye nezinye iimpawu ezifana negazi. Ukuba ishiywe inganyangwa, isifo seengcongconi sinokubulala.

I-Artemeti isebenza kakhulu ngokuchasene nobunzima obunganyangekiyo ngamachiza kwi-plasmodium falciparum, enika i-akhawunti yokusweleka kwabantu abanxulumene nemalariya kwihlabathi liphela. Ikwasebenza nakwezinye iintlobo zePasismodium zePasmodium ezibangela imalariya. I-Artemether ihlala ilawulwa ngokudibeneyo kunye nezinye iziyobisi, ezinje nge-lumefantrine, ukunciphisa umngcipheko wokunganyangeki ngamachiza.

Ngaphandle kokusetyenziswa kwayo njengesiyobisi se-antimalales, i-artemeti ifunyenwe ineepropathi zonyango. Izifundo zibonakalise ukuba i-anti-insulelotory, i-anti-tumar, kunye nemisebenzi yentsholongwane. Isetyenziselwe ukuphatha i-Arthritis, i-Lupus, kunye nezinye izifo ze-autoimmune. Kukwaphandwa ngamandla ayo okunyanga iCoVid-19, nangona kufuneka uphando ngakumbi ukuqinisekisa ukusebenza kwalo.

I-Artemeti ikhuselekile kwaye inyamezelekile xa isetyenziswa njengoko kuyalelwe. Nangona kunjalo, njengazo zonke iziyobisi, kunokubangela iziphumo ebezingalindelekanga. Ezona ziphumo ziqhelekileyo ze-artemeting ziquka isicaphucaphu, ukugabha, isiyezi, kunye nentloko. Kwiimeko ezinqabileyo, kunokubangela ukuba izinto ezigwenxa ziqaqambileyo, ezinjengeentliziyo zentliziyo, ukuzibamba, kunye nomonakalo wesibindi.

Ukuqukumbela, i-artemether sisiyobisi esisebenzayo esine-antimalalatial esingenayo inyameko yonyango lwesifo seengcongconi kunye nokuthintela. Ukufunyanwa kwayo kusingise ubomi obungenakubalwa kwaye wafumana ukuqonda kuluntu lwezenzululwazi. Ezinye iipropathi zonyango zenza ukuba umgqatswa othembisayo ukuze afumane ezinye izifo. Nangona kunokubangela iziphumo ebezingalindelekanga, izibonelelo zayo zidlula kude kumngcipheko wayo xa zisetyenziswa phantsi kweliso kwezonyango.
Iifom ze-dosage ezisetyenziswayo zibandakanya iitafile, iicaphule kunye nenaliti. Iindidi zeziyobisi ziziyobisi ze-antimalalial, kwaye eyona nto iphambili yi-artemether. Umlinganiswa ongumlinganiso weetafile ze-artemese yayingamacwecwe amhlophe. Uphawu lwe-artemether capsule yipikile, iziqulatho zokuba ngumgubo omhlophe; Uhlobo lweziyobisi lwenaliti ye-artemether ingenabala ingenabala kwioyile ephuzi etyheli-njengolwelo.