I-Niacin

I-Niacin, okanye i-vitamin B3, yenye yeevithamini ezibalulekileyo ze-B-complex ezinyibilikayo emanzini ezifunekayo emzimbeni ukuze ziguqule ukutya kube ngamandla. Zonke iivithamini kunye neeminerali zibalulekile kwimpilo entle, kodwa i-niacin ilungile ngakumbi kwiinkqubo zemithambo-luvo kunye nezokugaya ukutya. Masijonge ngokunzulu ukuze siqonde ngcono iingenelo ze-niacin kunye nemiphumo yayo emibi.

I-Niacin ikhona ngokwemvelo kwiintlobo ezininzi zokutya kwaye ifumaneka kwi-supplement kunye nefomu kagqirha, ngoko ke kulula ukufumana i-niacin eyaneleyo kwaye ufumane iingenelo zayo zempilo. Izicubu emzimbeni ziguqula i-niacin ibe yi-coenzyme esebenzisekayo ebizwa ngokuba yi-nicotinamide adenine dinucleotide (NAD), esetyenziswa zii-enzymes ezingaphezu kwama-400 emzimbeni ukwenza imisebenzi ebalulekileyo.

Nangona ukunqongophala kwe-niacin kunqabile kubantu base-United States, kunokuba nzima kakhulu kwaye kubangele isifo esiqhelekileyo esibizwa ngokuba yi-pellagra. Amatyala amancinci e-pellagra anokubangela urhudo kunye ne-dermatitis, ngelixa amatyala anzima ngakumbi anokubangela i-dementia kwaye ade afe.

I-Pellagra ixhaphake kakhulu kubantu abadala abaphakathi kweminyaka engama-20 ukuya kwengama-50 ubudala, kodwa inokuthintelwa ngokutya i-niacin ecetyiswayo. I-RDA yabantu abadala ye-niacin yi-14 ukuya kwi-16 mg ngosuku. I-Niacin ifumaneka ngokulula ekutyeni okufana nentlanzi, inkukhu, inyama yenkomo, i-turkey, iziqhamo kunye nemifuno. I-Niacin inokwenziwa emzimbeni nge-amino acid tryptophan. Le amino acid ifumaneka ekutyeni okufana nenkukhu, i-turkey, amantongomane, imbewu kunye neemveliso zesoya.

I-Niacin ikwafumaneka kwii-multivitamin ezininzi ezithengiswa ngaphandle kwemithi njengesongezelelo sokutya. Zombini ii-Nature Made kunye ne-Centrum adult multivitamins ziqulathe i-20 mg ye-niacin kwithebhulethi nganye, emalunga ne-125% ye-RDA yabantu abadala. I-Nicotinic acid kunye ne-nicotinamide ziintlobo ezimbini zezongezo ze-niacin. Izongezo ze-niacin ezithengiswa ngaphandle kwemithi zifumaneka ngamandla ahlukeneyo (50 mg, 100 mg, 250 mg, 500 mg) aphezulu kune-RDA. Iintlobo ze-niacin ezimiselwe ngugqirha ziquka amagama eempawu ezifana ne-Niaspan (extended-release) kunye ne-Niacor (i-immediate-release) kwaye zifumaneka ngamandla afikelela kwi-1,000 mg. I-Niacin inokufumaneka kwifomyula ekhutshwa ngokukhawuleza ukunciphisa ezinye iziphumo ebezingalindelekanga.

Ngamanye amaxesha i-niacin inikwa kunye namayeza okunciphisa i-cholesterol afana nee-statins ukunceda ekulungiseni amanqanaba e-lipid egazini.

Obunye ubungqina bubonisa ukuba i-niacin ilungile kubantu abanomngcipheko ophezulu wokuhlaselwa sisifo sentliziyo kunye nesifo sentliziyo kuba ayithobeli nje kuphela i-LDL cholesterol kodwa ikwathomalalisa ne-triglycerides. I-Niacin inokunciphisa amanqanaba e-triglyceride ngama-20% ukuya kuma-50%.