Kutshanje, i-Akay Bioactives, umenzi wezithako zesondlo wase-US, upapashe uphononongo olungahleliwe, olulawulwa yi-placebo malunga neziphumo zezithako ze-Immufen™ kwi-rhinitis ye-allergic rhinitis, icomplex ye-turmeric kunye ne-tomato enxilileyo yaseMzantsi Afrika. Iziphumo zophononongo zibonise ukuba i-turmeric kunye ne-South African extracts ezinxilisayo zinokukhulula i-rhinitis ye-allergen.
I-Allergic Rhinitis, inkxalabo yezempilo yabantu abangaphezu kwezigidi ezingama-400
I-Allergic rhinitis (AR) sisifo esixhaphakileyo sokudumba kwendlela ephezulu yokuphefumla esichaphazela abantu abangaphezu kwezigidi ezingama-400 kwihlabathi liphela, kwaye ukuxhaphaka kwaso kunyukile kule minyaka imbalwa idlulileyo. Iimpawu zayo ziquka ukuthimla, impumlo evuzayo, ukuxinana kweempumlo, ukurhawuzelelwa kwamehlo, impumlo nenkalakahla. Ngokuqhelekileyo i-comorbid nezinye iimeko ezifana ne-asthma, conjunctivitis, kunye ne-sinusitis, enokukhokelela ekunciphiseni umgangatho wobomi, ukungasebenzi kakuhle kwengqondo, ukusebenza kakubi komsebenzi, kunye nomgangatho ophantsi wokulala.
Iindlela eziphambili kwi-pathogenesis ye-rhinitis ye-allergic ukungalingani phakathi kohlobo lwe-1 umncedisi we-T cells (Th1) kunye nohlobo lwe-2 umncedisi we-T cell (Th2), kunye nokungalingani phakathi kwe-innate and adaptive immunity kubandakanywa iiseli ze-antigen-presenting, i-lymphocytes kunye neeseli ze-T.
Unyango lwe-rhinitis ye-allergies luhlala lwenziwa ngokusebenzisa i-antihistamines okanye i-decongestants ye-nasal, kwaye nangona i-antihistamines iye yaphuculwa kwizizukulwana ezininzi, isenokubangela uluhlu lwemiphumo emibi efana nentloko, ukukhathala, ukozela, i-pharyngitis, kunye nesiyezi. Unyango lwe-Herbal ngoku luvela njengeyeza elikhuselekileyo okanye elinye iyeza lokuphucula kunye / okanye ukulawula iimeko ze-AR.
I-Turmeric + Iitumato ezinxilileyo zaseMzantsi Afrika Ziphucule ngokuphawulekayo i-AR
Kuphononongo olupapashwe ngu-Akay Bioactives, abathathi-nxaxheba be-105 babelwa ngokungenamkhethe ukuba bafumane i-turmeric extract kunye ne-South African drunken tomato extract (CQAB, i-capsule nganye ye-CQAB iquka i-95 ± 5 mg curcumin kunye ne-125 mg ye-tomato extract yaseMzantsi Afrika), i-curcumin ye-bioavailable (CGM), i-capsule nganye ye-CGM iqulethe i-250 mg curcumin), okanye i-placebo kabini imihla ngemihla Iintsuku ezingama-28. Ngohlalutyo lwe-covariance (ANCOVA), i-CQAB ifunyenwe ukunciphisa kakhulu iimpawu ezinxulumene ne-rhinitis ye-allergen xa kuthelekiswa ne-CGM kunye ne-placebo. Xa kuthelekiswa ne-placebo: ukuxinana kweempumlo kuncitshiswe ngama-34.64%, impumlo ebalekayo ngama-33.01%, impumlo erhawuzelelwa ngama-29.77%, ukuthimla ngama-32.76%, kunye neTotal Symptom Score (TNSS) ngama-31.62%; xa kuthelekiswa neCGM: ukuxinana kweempumlo kuncitshiswe nge-31.88%, impumlo ebalekayo ngo-53.13%, impumlo erhawuzelelwa ngama-24.98%, ukuthimla nge-2.93%, kunye nokuncipha kwe-25.27% kwiTotal Symptom Score (TNSS).
I-monograph ye-Ayurvedic i-Dhanwantari Nighantu ikhankanya i-turmeric njengokhuselo kunye nonyango lwe-rhinitis. I-eggplant enxilileyo isetyenziselwa ukunyanga ukuxinana kweempumlo (ukuyeka ukukhohlela kunye nobunzima bokuphefumla) kunye nokuphucula amandla. Ukudityaniswa kwezi zityalo zimbini kunokuba nefuthe le-synergistic pharmacological effect kwaye ngaloo ndlela kuphuculwe i-rhinitis ye-allergen.Akay Bioactives epapashiweyo uphando olufumene ukuba amandla e-curcumin okulungelelanisa amajoni omzimba axhomekeke ekusebenzisaneni kwawo kunye neentlobo ezahlukeneyo ze-immune modulators, ezifana neeseli ze-B, T. iiseli, iiseli zedendritic, iiseli ezibulalayo zendalo, iineutrophils, neemacrophages; kunye nokuba izithako ezisebenzayo ze-tomato yokunxila yaseMzantsi Afrika (i-tomato yokunxila i-lactone kunye ne-The active constituents of South African hepatica (i-hepatica lactone kunye ne-hepatica lactone glycosides) zinokusebenzisa iziphumo zazo zokugonywa komzimba ngokuhlanganisa kunye nokuvula i-macrophages.
Abantu abaneempawu ze-rhinitis ye-alergic badla ngokuba nomgangatho ophantsi wokulala, nto leyo enokukhokelela ekunciphiseni isakhono sokufunda, ukufunda okuphantsi/imveliso, kwaye ngaloo ndlela ubomi buphantsi. Ngelixa i-curcumin kwi-turmeric inokunciphisa i-latency yokulala kunye nokwandisa ixesha lokulala kwiigundane; ukunxila i-lactone ekunxileni kwaseMzantsi Afrika kunokuphelisa uxinzelelo kunye nokuphucula ukulala. Ngoko ke, kunokucingelwa ukuba iziphumo ze-synergistic zaseMzantsi Afrika ezinxilisayo kunye ne-curcumin zinokuthi zinike iziphumo zokukhuthaza ukulala kwe-CQAB.
Ukongezelela, abathathi-nxaxheba kwisifundo esipapashiweyo bachaza amanqanaba okwanda kokuphazamiseka kwemizwelo, ukukhathala, kunye nokunciphisa amandla ekuqaleni kwesifundo. Kwaye i-curcumin iphucule kakhulu isimo sengqondo esibi. Ngokufanayo, iSouth African Drunken Tomato Extract iyaziwa ngokunciphisa uxinzelelo kunye nokwandisa amandla, ngaloo ndlela iphucula umgangatho wobomi kunye nokukwazi ukusebenza emsebenzini. Phakathi kwezinye izinto, iiTomato ezinxilileyo zaseMzantsi Afrika zinokunciphisa ukusebenza kwe-hypothalamic-pituitary-adrenal axis (HPA) axis. Ukuphendula kwi-stimuli exinzelelekileyo, i-axis ye-HPA ngokungangqalanga igalelo ekugxininiseni okuphakamileyo kwe-cortisol kunye ne-dehydroepiandrosterone (DHEA), kunye namanqanaba aphantsi e-DHEA yimbangela yeengxaki ezininzi zengqondo, zengqondo kunye nezengqondo.
Usetyenziso lweMveliso yeTurmeric + yeeTomato ezinxilileyo zaseMzantsi Afrika
Idatha ye-Futuremarketinsights ityhila ukuba ubungakanani bemarike ye-turmeric yehlabathi bunokufikelela kwi-USD 4,419.3 yezigidi ngo-2023. Ukukhula kwi-CAGR ye-5.5% ngexesha loqikelelo (2023-2033), imarike iyonke iya kuxabiswa ngaphezulu kwe-USD 7,579.2 yezigidi ngo-2033.
Ngeli xesha, ubungakanani bemarike yemveliso enxilisayo yaseMzantsi Afrika bunokufikelela kwi-USD 698.0 yezigidi ngo-2023 kwaye kulindeleke ukuba ifikelele kwi-USD 1,523.0 yezigidi ngo-2033. Ikhula kwi-CAGR ye-8.1% ngexesha loqikelelo (2023-2033). Impembelelo ye-synergistic ye-turmeric kunye neziyobisi zaseMzantsi Afrika ibonakaliswe ukuba ineenzuzo ezibalulekileyo zempilo kwaye isetyenziswa kwiimveliso ezahlukeneyo.
Impilo entle njeingenziwa ngokwesambuku
(1) Isongezo esiqulethe i-turmeric kunye ne-South African hepatica, enokuthi ifakwe emanzini ashushu okanye ubisi kwaye isetyenziswe kunye. Yongeza ukhuselo lomzimba, amandla kunye nokunyamezela, ukulwa nemikhuhlane kunye nomkhuhlane, iphucula ukugaya kunye nombono.
(2) I-Supplement equkethe i-curcumin kunye ne-tomato yaseMzantsi Afrika enentloko, imveliso inokugcina abantu begcwele amandla, incede ukuzinzisa isimo sengqondo, kunye nokuqinisekisa impilo yamalungu kunye namanye amalungu omzimba.
(3) Umxube wezityalo oqulethe i-hepatica yaseMzantsi Afrika kunye ne-curcumin, ekhulula uxinzelelo olubangelwa uxinzelelo kunye nokugcina umoya wolonwabo.
(4) Iziselo eziqukethe i-turmeric kunye ne-cigars ezinxilisayo zaseMzantsi Afrika, ezingenayo iswekile eyongezelelweyo, zinceda abantu ukuba bakhulise ukucinga kwabo kunye nokugcina ukugxila.
Ixesha lokuposa: Nov-21-2024