Kutshanje, i-Akay Bioactives, umenzi wezithako zesondlo e-US, ipapashe uphando olucwangcisiweyo, olulawulwa yi-placebo malunga nemiphumo yesithako sayo se-Immufen™ kwi-rhinitis ebuthathaka, i-complex ye-turmeric kunye ne-tomato enxilileyo yaseMzantsi Afrika. Iziphumo zolu phononongo zibonise ukuba i-turmeric kunye ne-extracts ezinxilisayo zaseMzantsi Afrika zinokuphelisa i-rhinitis ye-allergy.
I-Allergic Rhinitis, ingxaki yempilo yabantu abangaphezu kwezigidi ezingama-400
I-Allergic rhinitis (AR) sisifo esiqhelekileyo sokudumba kwendlela yokuphefumla ephezulu esichaphazela abantu abangaphezu kwezigidi ezingama-400 kwihlabathi liphela, kwaye ukuxhaphaka kwaso kuye kwanda kwiminyaka embalwa edlulileyo. Iimpawu zaso ziquka ukuthimla, impumlo egobhozayo, ukuxinana kwempumlo, kunye nokurhawuzelelwa kwamehlo, impumlo, kunye nenkalakahla. Sidla ngokudibana nezinye izifo ezifana ne-asthma, i-conjunctivitis, kunye ne-sinusitis, ezinokukhokelela ekuncipheni komgangatho wobomi, ukungasebenzi kakuhle kwengqondo, ukusebenza kakubi komsebenzi, kunye nomgangatho wokulala ophantsi.
Iindlela eziphambili kwi-pathogenesis ye-allergy rhinitis kukungalingani phakathi kwee-type 1 helper T cells (Th1) kunye nee-type 2 helper T cells (Th2), kunye nokungalingani phakathi kwe-innate and adaptive immunity kuquka ii-antigen-presenting cells, ii-lymphocytes kunye nee-T cells.
Unyango lwe-allergy rhinitis ludla ngokwenziwa ngokusebenzisa ii-antihistamines okanye ii-decongestants zeempumlo, kwaye nangona ii-antihistamines ziye zaphuculwa kwizizukulwana ezininzi, zisenokubangela iziphumo ezahlukeneyo ezimbi ezifana nentloko ebuhlungu, ukudinwa, ukozela, i-pharyngitis, kunye nesiyezi. Unyango lwezityalo ngoku luvela njengeyeza elikhuselekileyo okanye elinolunye unyango lokuphucula kunye/okanye ukulawula iimeko ze-AR.
Iitamati ezinxilisiweyo zeTurmeric kunye nezaseMzantsi Afrika ziyiphucula kakhulu i-AR
Kolu phononongo lupapashwe yi-Akay Bioactives, abathathi-nxaxheba abali-105 babelwa ngokungacwangciswanga ukuba bafumane i-turmeric extract kunye ne-South African drunk tomato extract (i-CQAB, i-CQAB capsule nganye iquka i-95 ± 5 mg ye-curcumin kunye ne-125 mg ye-South African drunk tomato extract), i-bioavailable curcumin (i-CGM, i-CGM capsule nganye iqulethe i-250 mg ye-curcumin), okanye i-placebo kabini ngemini kangangeentsuku ezingama-28. Ngokuhlalutya i-covariance (ANCOVA), i-CQAB ifunyenwe inciphisa kakhulu iimpawu ezinxulumene ne-allergy rhinitis xa kuthelekiswa ne-CGM kunye ne-placebo. Xa kuthelekiswa ne-placebo: ukuxinana kwempumlo kuncitshisiwe ngama-34.64%, impumlo egobhozayo ngama-33.01%, impumlo erhawuzelela ngama-29.77%, ukuthimla ngama-32.76%, kunye ne-Total Nasal Symptom Score (TNSS) ngama-31.62%; xa kuthelekiswa ne-CGM: ukuxinana kweempumlo kuncitshiswe ngama-31.88%, impumlo egobhozayo ngama-53.13%, impumlo erhawuzelelwayo ngama-24.98%, ukuthimla ngama-2.93%, kunye nokwehla ngama-25.27% kwiTotal Nasal Symptom Score (TNSS).
I-monograph ye-Ayurvedic uDhanwantari Nighantu ukhankanya i-turmeric njengokhuselo kunye nonyango lwe-rhinitis. I-eggplant enxilileyo isetyenziselwa ukunyanga ukuxinana kwempumlo (ukuyeka ukukhwehlela kunye nobunzima bokuphefumla) kunye nokuphucula amandla. Ukudibana kwezi zityalo zimbini kunokuba nefuthe le-synergistic pharmacological kwaye ngaloo ndlela kuphucule i-allergy rhinitis. I-Akay Bioactives ipapashe uphando olufumanise ukuba amandla e-curcumin okuguqula inkqubo yomzimba axhomekeke ekusebenzisaneni kwayo nee-immune modulators ezahlukeneyo, ezifana nee-B cells, ii-T cells, ii-dendritic cells, ii-natural killer cells, ii-neutrophils, kunye nee-macrophages; kwaye izithako ezisebenzayo zetamatato enxilisayo yaseMzantsi Afrika (i-drunkenness tomato lactone kunye ne-The active components ye-South African hepatica (hepatica lactone kunye ne-hepatica lactone glycosides) zinokusebenzisa imiphumo yazo yokuguqula umzimba ngokuhlanganisa kunye nokusebenzisa ii-macrophages.
Abantu abaneempawu ze-allergy rhinitis badla ngokuba nomgangatho ophantsi wokulala, nto leyo enokubangela ukuba amandla okufunda anciphe, ukufunda/imveliso iphantsi, ngaloo ndlela ubomi bube kumgangatho ophantsi. Ngelixa i-curcumin kwi-turmeric inokunciphisa ixesha lokulala kwaye yonyuse ixesha lokulala kwiimpuku; ukunxila i-lactone ekunxileni eMzantsi Afrika kunokunciphisa uxinzelelo kwaye kuphucule ukulala. Ke ngoko, kunokucingelwa ukuba iziphumo zokunxibelelana kwezidakwa zaseMzantsi Afrika kunye ne-curcumin zisenokuba zibangele iziphumo zokukhuthaza ukulala ze-CQAB.
Ukongeza, abathathi-nxaxheba kolu phando lupapashiweyo baxele ukuba amanqanaba okwanda kweengxaki zeemvakalelo, ukudinwa, kunye nokuncipha kwamandla ekuqaleni kolu phando. Kwaye i-curcumin iphucule kakhulu imeko-bume engentle. Ngokufanayo, i-South African Drunken Tomato Extract yaziwa ngokunciphisa uxinzelelo kunye nokwandisa amandla, ngaloo ndlela iphucula umgangatho wobomi kunye nokukwazi ukusebenza emsebenzini. Phakathi kwezinye izinto, i-South African Drunken Tomatoes inokunciphisa umsebenzi we-hypothalamic-pituitary-adrenal (HPA) axis. Ukuphendula kwizikhuthazo zoxinzelelo, i-HPA axis ngokungathanga ngqo inegalelo ekuphakameni kwe-cortisol kunye ne-dehydroepiandrosterone (DHEA), kwaye amanqanaba aphantsi e-DHEA ayimbangela yeengxaki ezininzi zengqondo, zomzimba nezesondo.
Ukusetyenziswa kweTurmeric + Iitamatisi ezinxilisiweyo zaseMzantsi Afrika
Idatha ye-futuremarketinsights ityhila ukuba ubungakanani bemarike ye-turmeric yehlabathi bunokufikelela kwi-USD 4,419.3 yezigidi ngo-2023. Ikhula kwi-CAGR ye-5.5% ngexesha lexesha eliqikelelweyo (2023-2033), imakethi iyonke iya kuba nexabiso elingaphezulu kwe-USD 7,579.2 yezigidi ngo-2033.
Okwangoku, ubungakanani bemarike ye-intoxicant extract yaseMzantsi Afrika bunokufikelela kwi-USD 698.0 yezigidi ngo-2023 kwaye kulindeleke ukuba ifikelele kwi-USD 1,523.0 yezigidi ngo-2033. Ikhula kwi-CAGR ye-8.1% ngexesha lexesha eliqikelelweyo (2023-2033). Isiphumo sokusebenzisana kwe-turmeric kunye ne-intoxicants yaseMzantsi Afrika sibonakaliswe sineenzuzo ezibalulekileyo zempilo kwaye sisetyenziswa kwiimveliso ezahlukeneyo.
Impilo yeJustgoodingenziwa ngokwezifiso ngobuninzi
(1) Isongezelelo esine-turmeric kunye ne-hepatica yaseMzantsi Afrika, enokongezwa emanzini ashushu okanye ubisi kwaye ityiwe kunye. Yomeleza amasosha omzimba, amandla kunye nokunyamezela, ilwa nomkhuhlane kunye nomkhuhlane, iphucula ukugaya ukutya kunye nokubona.
(2) Isongezelelo esine-curcumin kunye neetamatisi ezinamazinyo zaseMzantsi Afrika, imveliso inokunceda abantu bahlale benamandla, incede ekuzinziseni imeko, kwaye iqinisekise impilo yamalungu kunye namanye amalungu omzimba.
(3) Umxube wezityalo oqulethe i-hepatica kunye ne-curcumin yaseMzantsi Afrika, onceda ukudakumba okubangelwa luxinzelelo kwaye ugcine umoya wolonwabo.
(4) Iziselo ezine-turmeric kunye neecuba ezinxilisayo zaseMzantsi Afrika, ezingenaswekile yongeziweyo, zinceda abantu ukuba baphucule indlela abacinga ngayo kwaye bahlale begxile.
Ixesha leposi: Novemba-21-2024