I-Alpha-Hydroxy-Isocaproic Acid (HICA)

I-HICA yenye yeekhompawundi ezininzi zendalo, ezisebenzayo, eziphilayo, ezifumaneka emzimbeni, ezithi xa zinikezelwa njengesongezelelo, ziphucule kakhulu ukusebenza komntu -- i-creatine ngomnye umzekelo onjalo.
I-HICA sisifinyezo se-alpha-hydroxy-isocaproic acid. Ikwabizwa ngokuba yi-leucic acid okanye i-DL-2-hydroxy-4-methylvaleric acid. Ukuba ungayibeki ecaleni i-nerd-speak, i-HICA ligama elilula kakhulu ukulikhumbula, kwaye eneneni yenye yezithako ezi-5 eziphambili kwimveliso yethu ye-MPO (Muscle Performance Optimizer).
Ngoku, oku kungabonakala ngathi yinto engaqhelekanga kodwa hlala nam umzuzwana. I-amino acid leucine ivuselela i-mTOR kwaye ibalulekile ekuvuseleleni ukwenziwa kweproteni yemisipha, nto leyo engundoqo ekwakheni izihlunu okanye ekuthinteleni ukuqhekeka kwezihlunu. Usenokuba ukhe weva nge-leucine ngaphambili kuba zombini ziyi-BCAA (branched-chain amino acid) kunye ne-EAA (essential amino acid).
Umzimba wakho uvelisa i-HICA ngokwendalo ngexesha le-metabolism ye-leucine. Izihlunu kunye nezicubu ezinxibelelanayo zisebenzisa kwaye zigaya i-leucine ngenye yeendlela ezimbini ezahlukeneyo ze-biochemical.
Indlela yokuqala, indlela ye-KIC, ithatha i-leucine ize idale i-KIC, i-intermediate, ethi kamva iguqulwe ibe yi-HICA. Enye indlela ithatha i-leucine ekhoyo ize idale i-HMB (β-Hydroxy β-methylbutyric acid). Ngoko ke, izazinzulu zibiza i-HICA, kunye nomzala wayo owaziwayo i-HMB, ngokuba yi-leucine metabolites.
Izazinzulu zicinga ukuba i-HICA yi-anabolic, nto leyo ethetha ukuba iphucula ukwenziwa kweproteni yemisipha. Ingakwenza oku ngeendlela ezahlukeneyo, kodwa izifundo zibonisa ukuba i-HICA yi-anabolic kuba ixhasa ukusebenza kwe-mTOR.
I-HICA ikwatyalwe ukuba ineempawu zokulwa ne-catabolic, oko kuthetha ukuba inceda ekuthinteleni ukuqhekeka kweeproteni zemisipha ezifumaneka kwizicubu zemisipha.
Njengoko uzilolonga ngamandla, izihlunu zakho zifumana i-micro-trauma ebangela ukuba iiseli zemisipha ziqhekeke. Sonke siziva iziphumo zale micro-trauma emva kweeyure ezingama-24-48 emva kokuzilolonga ngamandla ngendlela yokudakumba kwemisipha okulibazisekayo (DOMS). I-HICA iyayinciphisa kakhulu le ngxaki okanye i-catabolism. Isiphumo soku kukuba i-DOMS encinci, kwaye izihlunu ezithambileyo zakhiwe phezu kwayo.
Ngoko ke, njengesongezelelo, izifundo zibonisa ukuba i-HICA ayichaphazeli abantu abakhubazekileyo. Kubo bonke abafuna ukuphucula ukusebenza kwabo kwezemidlalo, kufuneka basebenzise izongezo ezibonisa ukuba ziyanceda abantu abakhubazekileyo.